Quantum Computing for Multi-Omics Data Integration in Bioengineering Applications

Abstract

Integrating the various omics to conduct a thorough research of biological systems is known as multi-omics. It enables a comprehensive comprehension of the intricate relationships and dynamics that exist within an organism. Understanding complicated biological systems and developing bioengineering applications like disease modelling, metabolism engineering, & precision medicine depend on integrating of multi-omics data. However, traditional computational methods are severely hampered by the high complexity, heterogeneity, & nonlinear interactions among genomes, genomics, proteomics, and metabolomics data. In order to effectively describe intricate cross-omics interactions, this research proposes a quantum computing-based framework for multiple-omics data integration that makes use of the concepts of quantum juxtaposition and entanglement. A hybrid cognitive–classical architecture is suggested, wherein classical optimisation methods are used for training and multi-omics features are converted into states of matter and processed utilising variational quantum circuits. Phenotype prediction and route analysis are two downstream bioengineering tasks that make use of the integrated quantum representations. In comparison to classical approaches, the suggested strategy delivers better integration efficiency and prediction performance, as demonstrated by experimental assessments utilising simulated quantum settings. The findings demonstrate quantum computing's promise as a potent instrument for precise and scalable multi-omics data integration, opening the door for applications in systems biology and bioengineering of the future.